Imperial College London

Imperial College London have innovated solid-phase peptide synthesis (SPPS) to allow the synthesis of multiple peptide fragments on a single bead, departing from the conventional method of synthesising only one fragment per bead. This advancement promises to significantly boost the productivity of existing peptide analogues and facilitate the synthesis of first-in-class analogues.

https://www.ncl.ac.uk/pharmacy/people/profile/othmanalmusaimi.html

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Plasma2X

Plasma2X have developed a revolutionary plasma electrocatalysis technology for sustainable and efficient green ammonia and fertiliser production under ambient conditions. This emerging technology can accommodate a high turndown ratio and rapid start-up and shutdown, offering great flexibility for decentralised ammonia production using intermittent renewable energy.

https://p2xinnovations.com/

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Queen Mary, University of London

Queen Mary, University of London have developed a highly water repellent coating from 100% plant-based materials with antifouling and self-cleaning properties. The coatings provide the same barrier layer protection to water that is currently offered by plastics and therefore, on biodegradable substrates, can act as a compostable alternative to single use plastic packaging. 

https://www.sems.qmul.ac.uk/

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University College London

The carbon recycling technology (CART) developed by UCL scientists is a distributed cleantech platform that combines small, modular on-site advanced recycling, material value recovery, and real-time data and insights, aimed at giving healthcare facilities and medical waste handlers a comprehensive end-to-end solution for end-of-use plastic waste.

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University of Leeds

University of Leeds have developed LowCat, a new material for removing toxic gasses including nitrogen oxides and carbon monoxide from vehicle exhausts. LowCat functions at temperatures common in slow moving vehicles, where conventional emissions management technologies are not effective. LowCat does not use expensive platinum group metals, and is simple to manufacture.

https://www.leeds.ac.uk/lowcat

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University of Nottingham

Protein footprinting is a novel technology for mapping the binding sites of pharmaceutical, biotherapeutic and agrochemical products onto their protein target, at low cost and with high spatial resolution. Understanding how biologically active chemicals bind to proteins relevant to plant, animals and humans is critical to early-stage R&D of products.

www.photene.co.uk

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Eutechtics

Eutechtics have designed a catalytic chemical process for synthesizing "ultra-low carbon footprint" carboxylic acids from CO2 using bio-based deep eutectic solvents (DES). EvoCarbon operates at significantly milder temperatures and pressures than industrial methods, facilitates product isolation, material recycling, and reduces costs due to energy consumption.

https://eutechtics.com

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Heriot-Watt University

Rockit prevents evidently significant leaks of greenhouse gases for millennia by sealing porous rocks, fractures and fissures deep around wellbores with an acid-resistant mineral. It can be used for CCUS and hydrogen storage, addressing an ongoing global challenge of plugging thousands of existing and new wells quicker, better and safer.

http://rockit.rocks

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Leaf-tech

Leaf-tech's self-respiring membrane technology, which separates CO2 efficiently without the need for applied pressure, also delivers world-leading separation performance. This breakthrough significantly reduces the cost of direct air capture to under £150. Designed for scalability, our DAC system, built on this membrane, demands minimal maintenance yet ensures high performance.

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Pipeline Organics

Pipeline Organics' enzymatic biofuel cell, TankArc, generates direct current from the untapped resource of liquid organic waste in the food and beverage and other industries. TankArc’s enzymatic coating over its high 3D-printed surface area can be customised for individual customer waste profiles, providing clean, weather-independent, year-round electricity to user electrical plant. 

https://pipelineorganics.co.uk/

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University College London

The University of College London's technology introduces a safe, aqueous electrolyte with trace inorganic ammonium salts for high-power batteries. It shields the anode during fast charging, ensuring smooth zinc deposition. This approach delivers a safe, high-performance battery, ideal for various applications, from gadgets to renewable energy storage.

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University of Cambridge

Hydrogen is a promising carbon-free fuel but its current production methods rely on fossil methane or expensive electrolysers. In contrast, H2Upgrade converts zero-value industrial wastes into high-purity H2, enabling the waste-producing companies to become H2 producers and consumers, thus, promoting the H2 economy and distributed manufacturing.

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PlantSea Ltd

Plastic-free water-soluble packaging, made from seaweed

PlantSea have developed a highly innovative, environmentally-friendly alternative to plastic packaging. PlantSea water-soluble film is the only natural and plastic-free product that rivals the performance of PVOH for packaging laundry, cleaning, and personal care products (PVA/PVOH is a conventional water soluble plastic that causes significant microplastic pollution). 

https://plantsea.co.uk/  

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AquaYell

AquaYell have developed a process for the destruction of PFAS (per- and poly-fluorinated alkyl substances) using sonolysis (ultrasound cavitation). This process is catalyst- and chemical-free, robust for a wide range of solution matrices and produces no toxic effluent. Their process is highly scalable and is suitable for in-situ deployment.

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BindEthics

BindEthics have developed innovative food waste-derived Bio-adhesives to replace formaldehyde-based glues used to make engineered-wood products such as furniture. Formaldehyde-based adhesives, the industry standard, are toxic, carcinogenic, and the reason why wood panels are not recyclable. Their sustainable solution, not derived from fossil fuels, reduces the CO2 footprint by 86%.

www.bindethics.com

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Deakin Bio

Deakin Bio have developed a process to produce bio-based materials that are functionally equivalent to decorative ceramic tiles but avoid the need for high-temperature firing. This reduces the embodied carbon by approximately 94%. The bioinspired materials have a structure and chemistry similar to natural seashells, yet can be produced at scale.

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Protonera

Protenera's proprietary technology promises profitable waste recycling by turning waste plastics into green hydrogen and other valuable organic molecules. They use novel catalysts that are functional at ambient conditions with high tolerance to feedstock impurities. Protpnera's technology promises a one-stop waste elimination method to increase the post-consumer plastic recycling rate.

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ThioTech

ThioTech utilise the low-cost and abundant industrial waste product, elemental sulfur, combined with sustainably sourced chemicals, to make high sulfur content materials that can be used as next-generation absorbents to remove toxic metal residues from water, oil, and gas, thereby preventing environmental release and contamination, potentially outperforming incumbent technologies.

www.thiotech.co.uk

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Cardiff University

Cardiff University have developed a low-cost, photocatalyst-infused textile incorporated into the top layer of a reusable menstrual product. This textile has self-sanitising properties when exposed to sunlight, creating a safer product that reduces the risk of genitourinary tract infections, improving the lives of women and girls in the global south.

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University of Bristol

The University of Bristol have developed a rapid, sensitive, and versatile bacterial detection platform using functionalised gold nanoparticles through a simple colourimetric shift from a minimal sample volume. This innovative technology has the potential for diverse applications in areas such as healthcare, food safety, agriculture, aquaculture, manufacturing and environmental monitoring.

www.dyador.com 

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Ignota Labs

Ignota Labs have developed a novel AI platform to understand the root causes of safety problems in drug discovery. By combining Deep Learning models to predict how the drug interacts with the body, with algorithms over complex data, we can understand the biological impact of those interactions, enabling drug failure turnaround.

ignotalabs.ai

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University of Liverpool

The University of Liverpool have pioneered the designs and synthesis of a new class of antibiotics. Our synthesis platform is robust, automated, and scalable and uses low-cost goods. Synthetic teixobactins kill resistant bacterial pathogens without detectable resistance and have the potential to provide new treatment options to save countless lives globally.

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University of Oxford

University of Oxford have developed short peptides able to bind and neutralise the chemokine signalling network involved in inflammation. The peptides were developed from naturally occurring tick salivary proteins and functionalised using a rational drug design approach. Multi/Pan-chemokine inhibition aims to selectively inhibit pathological (autoimmune and) inflammatory responses without compromising wider immunity.

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Vector Bioscience Cambridge

Vector employs advanced porous nano shuttles, known as metal-organic frameworks (MOFs), to revolutionize cancer treatment. Their platform allows for precision medicine and drug delivery, minimising side effects by enabling targeted and controlled release of therapeutics, from small to macromolecules, including RNAs. This approach promises to significantly improve patient outcomes.

https://vectorbiocam.com/

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