Ignota Labs

SAFEPATH: Causal AI-driven mechanistic understanding of drug safety failures
 
2024 Health winner
Ignota Labs have developed a novel AI platform to understand the root causes of safety problems in drug discovery. By combining Deep Learning models to predict how the drug interacts with the body, with algorithms over complex data, we can understand the biological impact of those interactions, enabling drug failure turnaround.

ignotalabs.ai
“We're currently raising our seed round so being able to tell investors that we've won such a prestigious award from this institution is definitely going to help us along our way and really give that validation that we need.”

Layla Hosseini-Gerami, Chief Data Science Officer, Ignota Labs

BerryCells LtD

From light to logic: printed photocapacitors replacing billions of batteries

Energy

BerryCells harnesses earth-abundant copper coordination polymers to harvest indoor light and store energy in a single printable device. By co-designing molecular structure with computational power budgets, our photocapacitor delivers the exact microjoules an edge-AI chip needs per inference, eliminating batteries from wireless sensors and enabling perpetual smart monitoring.

www.berrycells.com


 

Our finalists

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University of Glasgow

Green_Nitrofix Technology for nitrogen fertilizer from air and water only

Enabling Technologies

Our technology is a device that allows farmers to produce their own nitrogen fertiliser directly on the farm using only air, water, and electricity without chemical handling. This enable farmers to make their own fertiliser on-site any time and anywhere.

www.gla.ac.uk


 

Our finalists

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Terrella Plasma Ltd

Plasma jet based metal deposition for next generation printed electronics

Enabling Technologies

We have developed a single step, non-contact metal printing capability that produces highly conductive, strongly adherent metal features on virtually any surface. This capability enables additive manufacture of interconnects on conformal surfaces and complex electronic sensors, without the high temperatures required by conventional methods.

www.terrella.app


 

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PlantSea

Plastic-free water-soluble films to replace PVOH for packaging applications

 
2025 Environment winner

Plantsea have developed a unique and scalable seaweed biorefining process to produce a new raw material to replace PVA/PVOH for the encapsulation of laundry detergents and chemicals. The product is cost comparative with PVOH, elastic, heat sealable, has a long shelf life, and is compliant with dissolution standards.

 

https://plantsea.co.uk/  

 

“The standard of competition, the technologies that everybody's working on this year are so incredible, so amazing, so we’re really grateful, and a bit in shock. The prestige is immense for us. We're currently going through an investment round, so hopefully it's something that really helps us finish off. And of course, the cash is always super helpful for a startup company. It’ll help with legal fees, as we'd like to file a couple more patents, and we're now doing some more commercial deals with some potential customers, but also it will fund some key trials that we need to do.”

Alex Newnes, CTO and Co-Founder, Plantsea
 
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Imperial College London

Electro-recycling of spent batteries for sustainable critical materials supply chain

Energy

We have developed a sustainable electro-recycling technology that selectively recovers high-value materials from end-of-life lithium-ion batteries. Using electricity instead of harmful chemicals, the process produces battery-grade materials for reuse, addressing critical mineral supply shortages, reducing carbon emissions, and enabling a circular battery supply chain to support net-zero goals.

https://profiles.imperial.ac.uk/xiaochu.wei16


 

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MetalMorph

On-site water treatment coagulant recovery and reuse via electrochemical separation.

Environment

Metal Morph's process recovers 90% of metal-based coagulants from drinking water treatment sludge at 95% purity using a novel electrochemical treatment train. The recovered chemicals are reused on-site, cutting utility chemical costs by 26%, reducing CO₂ emissions by up to 89% and eliminating landfill disposal of toxic waste.

https://metalmorph.co.uk/


 

Our finalists

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University of Manchester 

Ultra-efficient light-emitting materials for low-power display technologies

Energy

We have developed new molecular materials that produce light more efficiently in electronic devices, enabling brighter displays with lower power consumption. This reduces energy use and improves device performance, supporting next-generation low-power display and lighting technologies.

https://www.manchester.ac.uk/


 

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CDotBio

Sugar-based delivery platform enabling next-generation crop protection

Enabling Technologies

We have developed a sugar-based delivery platform that helps crop protection products work more effectively at lower doses. It improves uptake, stability, and performance of both biological and chemical solutions, enabling more sustainable, precise, and scalable agriculture without changing how farmers apply products.

https://www.cdotbio.co.uk/


 

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University of Birmingham

Turning PFAS waste into safe, reusable mineral fluorides

Environment

We have developed a solvent-free process that destroys PFAS by grinding them with metals, and converting them into stable, non-toxic mineral fluorides that can be reused in the chemical industry.

https://kubickilab.com/


 

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Demeter Bio Limited

Bio-based water and oil repellent coating for textiles

Environment

AguaShield is a biodegradable and bio-based coating that replaces toxic "forever chemicals" (PFAS) used to make textiles water- and oil-resistant. Made from biopolymers, it matches the performance of conventional coatings without harming the environment, and works with existing manufacturing equipment.

https://www.demeter-bio.com/


 

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Remedium Energy Ltd

Converting carbon-capture from a $100/tCO₂ liability into an $12/tCO₂ profit.

Energy

We're making carbon capture commercially viable, converting carbon capture from a $100/tCO₂ liability into an $12/tCO₂ profit opportunity. Our material captures 36x more CO₂, lowering material costs by 80%. Our Carbon-Capture-Heat-Battery enables low-cost regeneration using intermittent electricity with 24/7 heat supply, generating revenue from electricity arbitrage and heat sale.

https://www.remediumenergy.com/


 

Our finalists

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Terrella Plasma Ltd

Plasma jet based metal deposition for next generation printed electronics

Enabling Technologies

We have developed a single step, non-contact metal printing capability that produces highly conductive, strongly adherent metal features on virtually any surface. This capability enables additive manufacture of interconnects on conformal surfaces and complex electronic sensors, without the high temperatures required by conventional methods.

www.terrella.app


 

Our finalists

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R3V Tech

Green solvent from biodiesel waste— 50× value uplift.

Environment

R3V Tech developed a green process technology that enable undesired crude glycerol from biodiesel process to be converted into green solvent and high-value chemicals in a single step through electrochemical transformation, increasing 50 times its market value, reducing waste management burdens and creating circular economy opportunities for biodiesel producers.

www.r3vtech.com


 

Our finalists

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Brilliant Dyes

Low-energy, closed-loop algae dyes extraction and sustainable fixation in textiles

Environment

We have developed two patent pending technologies: a continuous low-energy, closed loop natural dyes extraction process and a sustainable dyes fixation using green chemicals. Together, it reduces energy use over 80%, cut water pollution in textile dyeing by 90% and saves the costs by 50% over other natural dyes.

https://www.brilliantdyes.com/


 

Our finalists

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University of Bath

Drugs for undruggable proteins using intracellular peptide discovery

Health

Revolver Therapeutics develops peptide drugs against “undruggable” proteins such as transcription factors. Our platform generates and tests drug candidates directly inside living cells, ensuring they are functional and cell-active. This enables new treatments for cancer and neurodegenerative diseases where conventional drug approaches have failed.

https://www.revolvertherapeutics.com/


 

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Cardiff Catalysis Institute

Hydro-Oxy: in-situ hydrogen peroxide synthesis for sustainable chemical production
2025 Enabling Technologies winner

Hydro-Oxy is a new innovative catalytic technology decoupling chemical synthesis from industrial hydrogen peroxide production. Generating hydrogen peroxide in-situ, we can achieve significant improvements in process intensification, safety and efficiency, reducing environmental impact and lowering manufacturing costs, whilst rivalling the performance metrics of the state-of-the-art industrial processes.   

 

 

 

“We’re absolutely flabbergasted. This is recognition of this technology and over 20 years of hard work from previous students and members of the team – it’s fantastic. The first thing is the recognition for such a prestigious award from the RSC. This will allow us to have very meaningful conversations and give us that clout, to show that we know what we’re doing and that we are a big players in this field.”

Richard Lewis, Entrepreneurial Lead, Hydro-Oxy (Cardiff Catalysis Institute)
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University of Liverpool

Electrified Plasma-Catalytic Technology for CO2 Conversion to Green Methanol

Energy

We have developed a patented plasma-catalytic process that efficiently converts CO2 and hydrogen into green methanol at 1 bar and 30 oC. This innovative technology eliminates the need for high temperatures and pressures, providing a flexible, modular solution that integrates renewable electricity for sustainable methanol production, with significantly reduced costs.

https://www.liverpool.ac.uk


 

Our finalists

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University of Manchester 

Ultra-efficient light-emitting materials for low-power display technologies

Energy

We have developed new molecular materials that produce light more efficiently in electronic devices, enabling brighter displays with lower power consumption. This reduces energy use and improves device performance, supporting next-generation low-power display and lighting technologies.

https://www.manchester.ac.uk/


 

Our finalists

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University of Bath

Probiosooth: probiotic modified fabrics for preventing and treating skin infection

Health

We have developed a technology which shows huge promise in preventing skin and wound infection by attaching 'good' bacteria probiotics (often added to yogurts and baby formula) to skin facing fabric. This has applications in infant care, care of adults with incontinence and chronic wound care.

http://www.bath.ac.uk


 

Our finalists

Take a look at the finalists across the four competition categories

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BerryCells LtD

From light to logic: printed photocapacitors replacing billions of batteries

Energy

BerryCells harnesses earth-abundant copper coordination polymers to harvest indoor light and store energy in a single printable device. By co-designing molecular structure with computational power budgets, our photocapacitor delivers the exact microjoules an edge-AI chip needs per inference, eliminating batteries from wireless sensors and enabling perpetual smart monitoring.

www.berrycells.com


 

Our finalists

Take a look at the finalists across the four competition categories.

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Lancaster University

OSPC: the new carbon material for safer, longer-lasting lithium-ion batteries

Energy

OSPC is a newly discovered porous carbon material that improves the safety and durability of lithium-ion batteries used in electric vehicles and renewable energy storage. When added in small amounts to graphite anodes, it suppresses lithium dendrite formation, reducing fire risk while remaining compatible with existing battery manufacturing processes.


 

Our finalists

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Lancaster University

OSPC: the new carbon material for safer, longer-lasting lithium-ion batteries

Energy

OSPC is a newly discovered porous carbon material that improves the safety and durability of lithium-ion batteries used in electric vehicles and renewable energy storage. When added in small amounts to graphite anodes, it suppresses lithium dendrite formation, reducing fire risk while remaining compatible with existing battery manufacturing processes.


 

Our finalists

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Percene Systems

Quantum-accurate training data platform for AI catalyst discovery

Enabling Technologies

Current AI tools for discovering catalysts are trained on inaccurate data, causing costly false leads in the lab. Percene's engine uses quantum computation to correct these errors, generating trustworthy training data for AI catalyst screenings. First demonstrated on CO₂ capture chemistry, Percene is making clean-chemistry discovery faster, cheaper, and more reliable.

Please note that this applicant was formerly known as "DeltaQ" and Emerging Technologies Competition marketing materials may reflect this initial application.

https://www.percene.com/


 

Our finalists

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Demeter Bio Limited

Bio-based water and oil repellent coating for textiles

Environment

AguaShield is a biodegradable and bio-based coating that replaces toxic "forever chemicals" (PFAS) used to make textiles water- and oil-resistant. Made from biopolymers, it matches the performance of conventional coatings without harming the environment, and works with existing manufacturing equipment.

https://www.demeter-bio.com/


 

Our finalists

Take a look at the finalists across the four competition categories

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Molecular Titans Ltd

Smart Polymer Platform for Instant Pathogen Detection with Handheld Devices

Health

Artemis™ is a patented smart-polymer material platform that physically captures and concentrates types of bacteria and fungi for instant detection. Working directly on large/mixed samples without laboratory culture, it delivers results in minutes across healthcare, food safety, and industrial settings, with cost-effective manufacturing already validated at the kilogram scale.

https://www.moleculartitans.org/


 

Our finalists

Take a look at the finalists across the four competition categories

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University of Glasgow

Green_Nitrofix Technology for nitrogen fertilizer from air and water only

Enabling Technologies

Our technology is a device that allows farmers to produce their own nitrogen fertiliser directly on the farm using only air, water, and electricity without chemical handling. This enable farmers to make their own fertiliser on-site any time and anywhere.

www.gla.ac.uk


 

Our finalists

Take a look at the finalists across the four competition categories

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University of Liverpool

Electrified Plasma-Catalytic Technology for CO2 Conversion to Green Methanol

Energy

We have developed a patented plasma-catalytic process that efficiently converts CO2 and hydrogen into green methanol at 1 bar and 30 oC. This innovative technology eliminates the need for high temperatures and pressures, providing a flexible, modular solution that integrates renewable electricity for sustainable methanol production, with significantly reduced costs.

https://www.liverpool.ac.uk


 

Our finalists

Take a look at the finalists across the four competition categories.

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Percene Systems

Quantum-accurate training data platform for AI catalyst discovery

Enabling Technologies

Current AI tools for discovering catalysts are trained on inaccurate data, causing costly false leads in the lab. Percene's engine uses quantum computation to correct these errors, generating trustworthy training data for AI catalyst screenings. First demonstrated on CO₂ capture chemistry, Percene is making clean-chemistry discovery faster, cheaper, and more reliable.

Please note that this applicant was formerly known as "DeltaQ" and Emerging Technologies Competition marketing materials may reflect this initial application.

https://www.percene.com/


 

Our finalists

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AlphaVectors Biotech

Fridge-free nanoparticles for global RNA-based vaccines and therapeutics delivery

Health

We have developed virus-inspired nanoparticles that deliver RNA-based vaccines and therapeutics without refrigeration. By mimicking how viruses naturally protect and deliver genetic material, our platform achieves room-temperature stability and lower doses, eliminating cold-chain dependence and making next-generation RNA medicines accessible to patients worldwide, including in low-resource settings.


 

Our finalists

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Demeter Bio Limited

Bio-based water and oil repellent coating for textiles

Environment

AguaShield is a biodegradable and bio-based coating that replaces toxic "forever chemicals" (PFAS) used to make textiles water- and oil-resistant. Made from biopolymers, it matches the performance of conventional coatings without harming the environment, and works with existing manufacturing equipment.

https://www.demeter-bio.com/


 

Our finalists

Take a look at the finalists across the four competition categories

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University of Manchester

DEUTEROSE: enabling research and diagnostics with clean cheap isotopic sugars

Enabling Technologies

Deuterose is a new biotechnology for clean manufacture of speciality isotopically labelled sugars. These sugars are essential for a range of research and medical applications, but their high cost makes them prohibitively expensive. Deuterose reduces costs by an order of magnitude - enabling frontier bioscience research and cutting edge diagnostic techniques.

https://www.deuterose.co.uk/


 

Our finalists

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R3V Tech

Green solvent from biodiesel waste— 50× value uplift.

Environment

R3V Tech developed a green process technology that enable undesired crude glycerol from biodiesel process to be converted into green solvent and high-value chemicals in a single step through electrochemical transformation, increasing 50 times its market value, reducing waste management burdens and creating circular economy opportunities for biodiesel producers.

www.r3vtech.com


 

Our finalists

Take a look at the finalists across the four competition categories

More info...

MetalMorph

On-site water treatment coagulant recovery and reuse via electrochemical separation.

Environment

Metal Morph's process recovers 90% of metal-based coagulants from drinking water treatment sludge at 95% purity using a novel electrochemical treatment train. The recovered chemicals are reused on-site, cutting utility chemical costs by 26%, reducing CO₂ emissions by up to 89% and eliminating landfill disposal of toxic waste.

https://metalmorph.co.uk/


 

Our finalists

Take a look at the finalists across the four competition categories

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Brilliant Dyes

Low-energy, closed-loop algae dyes extraction and sustainable fixation in textiles

Environment

We have developed two patent pending technologies: a continuous low-energy, closed loop natural dyes extraction process and a sustainable dyes fixation using green chemicals. Together, it reduces energy use over 80%, cut water pollution in textile dyeing by 90% and saves the costs by 50% over other natural dyes.

https://www.brilliantdyes.com/


 

Our finalists

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University of Liverpool

Synthetic Teixobactins: multitargeting antibiotics to combat resistant superbugs
 
2025 Health winner

The Univeristy of Liverpool have pioneered a robust, scalable, and automated synthetic platform to develop a new class of antibiotics—synthetic teixobactins. These antibiotics effectively eliminate drug-resistant bacterial pathogens without detectable resistance. Leveraging cost-effective components, our technology offers a compelling solution to antimicrobial resistance, potentially saving millions of lives around the world.

 

https://www.liverpool.ac.uk/people/ishwar-singh


“It's an amazing feeling. It was a very tough competition so I'm actually in shock at the minute that we won. This will have a huge impact for us in the sense that it gives us recognition, but also gives us a structure at the same time. We're already planning to open a spin-out, so this is going to help in the sense that I can free my time in lab and focus more on the business side of things.”

Anish Parmer, CEO and Co-Founder, University of Liverpool
 
 
More info...

University of Birmingham

Turning PFAS waste into safe, reusable mineral fluorides

Environment

We have developed a solvent-free process that destroys PFAS by grinding them with metals, and converting them into stable, non-toxic mineral fluorides that can be reused in the chemical industry.

https://kubickilab.com/


 

Our finalists

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Imperial College (FluoroCycle)

Breaking down PFAS “forever chemicals” with scalable low-energy destruction technology.

Environment

We have developed a chemical process capable of destroying a broad range of PFAS “forever chemicals”. This chemical destruction approach breaks down PFAS at 10x lower temperatures than high temperature incineration (HTI) and uses simple reagents to fully mineralise PFAS into fluoride salts. Low energy and affordable PFAS elimination onsite.


 

Our finalists

Take a look at the finalists across the four competition categories

More info...

Percene Systems

Quantum-accurate training data platform for AI catalyst discovery

Enabling Technologies

Current AI tools for discovering catalysts are trained on inaccurate data, causing costly false leads in the lab. Percene's engine uses quantum computation to correct these errors, generating trustworthy training data for AI catalyst screenings. First demonstrated on CO₂ capture chemistry, Percene is making clean-chemistry discovery faster, cheaper, and more reliable.

Please note that this applicant was formerly known as "DeltaQ" and Emerging Technologies Competition marketing materials may reflect this initial application.

https://www.percene.com/


 

Our finalists

Take a look at the finalists across the four competition categories

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Imperial College (FluoroCycle)

Breaking down PFAS “forever chemicals” with scalable low-energy destruction technology.

Environment

We have developed a chemical process capable of destroying a broad range of PFAS “forever chemicals”. This chemical destruction approach breaks down PFAS at 10x lower temperatures than high temperature incineration (HTI) and uses simple reagents to fully mineralise PFAS into fluoride salts. Low energy and affordable PFAS elimination onsite.


 

Our finalists

Take a look at the finalists across the four competition categories

More info...

AlphaVectors Biotech

Fridge-free nanoparticles for global RNA-based vaccines and therapeutics delivery

Health

We have developed virus-inspired nanoparticles that deliver RNA-based vaccines and therapeutics without refrigeration. By mimicking how viruses naturally protect and deliver genetic material, our platform achieves room-temperature stability and lower doses, eliminating cold-chain dependence and making next-generation RNA medicines accessible to patients worldwide, including in low-resource settings.


 

Our finalists

Take a look at the finalists across the four competition categories

More info...

University of Manchester

DEUTEROSE: enabling research and diagnostics with clean cheap isotopic sugars

Enabling Technologies

Deuterose is a new biotechnology for clean manufacture of speciality isotopically labelled sugars. These sugars are essential for a range of research and medical applications, but their high cost makes them prohibitively expensive. Deuterose reduces costs by an order of magnitude - enabling frontier bioscience research and cutting edge diagnostic techniques.

https://www.deuterose.co.uk/


 

Our finalists

Take a look at the finalists across the four competition categories

More info...

Remedium Energy Ltd

Converting carbon-capture from a $100/tCO₂ liability into an $12/tCO₂ profit.

Energy

We're making carbon capture commercially viable, converting carbon capture from a $100/tCO₂ liability into an $12/tCO₂ profit opportunity. Our material captures 36x more CO₂, lowering material costs by 80%. Our Carbon-Capture-Heat-Battery enables low-cost regeneration using intermittent electricity with 24/7 heat supply, generating revenue from electricity arbitrage and heat sale.

https://www.remediumenergy.com/


 

Our finalists

Take a look at the finalists across the four competition categories.

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NANOPLUME

Scalable Bio-Aerogel platform for cold chain and thermal insulation applications
 
2025 Energy winner

Nanoplume are scaling the manufacturing of Bio-Aerogel, a nanoporous, ultra-light biomaterial with industry-leading thermal insulation. Initially engineered for cold chain packaging, its fine-tuned structure ensures precise temperature control across logistics, packaging, and construction. Made from renewable feedstocks, it enhances energy and space efficiency whilst promoting circularity in sustainable thermal applications.

 

https://plantsea.co.uk/  

 

“It's a very nice recognition from a prestigious institution like the Royal Society of Chemistry. It's actually kind of a push and we feel that we are doing really well, so we are very happy with this kind of recognition.”

Theresa Hoffmann, CEO and Co-Founder,NANOPLUME
More info...

CDotBio

Sugar-based delivery platform enabling next-generation crop protection

Enabling Technologies

We have developed a sugar-based delivery platform that helps crop protection products work more effectively at lower doses. It improves uptake, stability, and performance of both biological and chemical solutions, enabling more sustainable, precise, and scalable agriculture without changing how farmers apply products.

https://www.cdotbio.co.uk/


 

Our finalists

Take a look at the finalists across the four competition categories

More info...

Imperial College (FluoroCycle)

Breaking down PFAS “forever chemicals” with scalable low-energy destruction technology.

Environment

We have developed a chemical process capable of destroying a broad range of PFAS “forever chemicals”. This chemical destruction approach breaks down PFAS at 10x lower temperatures than high temperature incineration (HTI) and uses simple reagents to fully mineralise PFAS into fluoride salts. Low energy and affordable PFAS elimination onsite.


 

Our finalists

Take a look at the finalists across the four competition categories

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ConsoneAI Ltd.

AI-platform predicting drug toxicity across animal species and human demographics

Health

We have developed DioScor an AI powered platform that predicts drug toxicity across multiple animal species and human demographics in under 90 seconds. Working within the existing drug development pathway, it helps drug developers make better go/no-go decisions earlier, reducing animal use, saving billions and protecting patients.

www.consoneAI.com


 

Our finalists

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Molecular Titans Ltd

Smart Polymer Platform for Instant Pathogen Detection with Handheld Devices

Health

Artemis™ is a patented smart-polymer material platform that physically captures and concentrates types of bacteria and fungi for instant detection. Working directly on large/mixed samples without laboratory culture, it delivers results in minutes across healthcare, food safety, and industrial settings, with cost-effective manufacturing already validated at the kilogram scale.

https://www.moleculartitans.org/


 

Our finalists

Take a look at the finalists across the four competition categories

More info...

University of Birmingham

Turning PFAS waste into safe, reusable mineral fluorides

Environment

We have developed a solvent-free process that destroys PFAS by grinding them with metals, and converting them into stable, non-toxic mineral fluorides that can be reused in the chemical industry.

https://kubickilab.com/


 

Our finalists

Take a look at the finalists across the four competition categories

More info...

University of Bath

Probiosooth: probiotic modified fabrics for preventing and treating skin infection

Health

We have developed a technology which shows huge promise in preventing skin and wound infection by attaching 'good' bacteria probiotics (often added to yogurts and baby formula) to skin facing fabric. This has applications in infant care, care of adults with incontinence and chronic wound care.

http://www.bath.ac.uk


 

Our finalists

Take a look at the finalists across the four competition categories

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Microsol Ltd

Aerosol engineering to derisk, accelerate and optimise inhaled drug development.

Health

Microsol is a Bristol-based aerosol technology company transforming inhaled drug development, to de-risk and accelerate the development process for pharmaceutical companies and produce better products for patients. Our approach combines predictive simulations with direct measurements of individual aerosol particles resulting in much faster, more accurate and cost-effective inhaled medicine development.

https://www.microsolscience.com/


 

Our finalists

Take a look at the finalists across the four competition categories

More info...